TECHNOLOGY
The MUQUABIS project is dedicated to advancing quantum-based technologies to transform biomedical research and diagnostics. By integrating state-of-the-art tools such as quantum frequency combs, non-classical infrared laser sources, and diamond-based magnetic microscopy, MUQUABIS aims to achieve unprecedented precision in studying biological structures and processes.
These technologies are designed to be non-invasive and highly sensitive, allowing for detailed insights into cellular and molecular behavior in ways that conventional methods cannot match. With applications ranging from cardiac health to molecular biology, MUQUABIS technologies set new standards in bioimaging and open pathways for innovative diagnostic tools that will impact healthcare and scientific understanding.
The MUQUABIS project develops advanced quantum technologies tailored to biomedical research and diagnostics, including:
NV MAGNETIC SENSING AND IMAGING
We aim at developing a comprehensive quantum magnetic sensing and imaging platform based on NV centers in diamond, tailored for the biological systems addressed in this proposal.
Achieving this goal will be comprised of the following objectives:
• Propose quantum control and analysis schemes for improved sensing
• Develop and realize advanced NV sensing techniques, including optimized diamond samples
• Implement bio-optimized NV sensing platform, distributed across the consortium
QUANTUM DUAL-COMB HYPERSPECTRAL-IMAGING AND SPECTROSCOPY
We explore the potential of quantum frequency combs and quantum-enhanced frequency comb spectro-imaging for biological sensing.
The following objectives will be pursued:
• Generation and characterization of novel quantum frequency combs based on entangled photon pairs
• Demonstration of dual-comb two-photonspectroscopy with entangled photon pairs using enhancement cavities
• Demonstration of sub-shot-noisecavity-enhanceddual-comblinear-absorptionspectro-imaging using squeezed vacuum fields and adaptation of the technique to biosensing.
DEVELOPMENT OF NON-CLASSICAL RADIATION SOURCES IN THE IR RANGE
We focus on the development and characterization of infrared light sources that will be used for quantum-enhanced imaging and spectroscopy applications.
Specifically, our objectives are:
• Development and characterization of laser sources with noise properties at the classical limit and beyond, squeezed light and photon pair sources from the near infrared to the THz spectral range, encompassing the whole IR range;
• Comparison of these sources with those already in operation to get quantitative data, on the basis of which the sources could undergo further improvement.
• Integration of selected new sources in specific quantum sensing set-ups and applications to specific biosamples.